Urinary Fibrinopeptide A in Evaluation of Patients with Suspected Acute Pulmonary Embolism (6)
As noted previously by others, the frequency distribution of FPA is log-normal. Therefore, logarithmic transformation was performed to obtain a normal, ie, gaussian, frequency distribution. The differences between the groups were then tested by the modified t test and a p value of less than 0.05 was considered significant. Thus, the uFPA data are in the form of their geometric means ± the geometric standard deviation (SD). Other data are expressed as the arithmetic means and SD. These data were analyzed using an unpaired t test. The true negative rate of the test was defined as the percentage of patients in whom PE was excluded who had a negative test result. Cheap Diskus Advair
Of the 100 consecutive patients, 71 were excluded: 64 with an abnormal V/Q scan, other than a high-probability interpretation, that was not defined further by PA; five patients receiving anticoagulants; and two patients who had undergone surgery within four days. The majority of the excluded patients (69 percent) had a V/Q scan interpreted as “low probability of PE,” which along with a clinical history was believed to be sufficient for exclusion of PE. There is evidence in the literature in support of this practice.
Twenty-nine patients were included in the final analysis: seven patients with PE (age range, 19 to 79 years, four female) and 22 who did not have PE (age range, 22 to 65 years, 15 female).