Medicine of the Future in America

Urinary Fibrinopeptide A in Evaluation of Patients with Suspected Acute Pulmonary Embolism (6)

Statistical Analyses
As noted previously by others, the frequency distribution of FPA is log-normal. Therefore, logarithmic transformation was performed to obtain a normal, ie, gaussian, frequency distribution. The differences between the groups were then tested by the modified t test and a p value of less than 0.05 was considered significant. Thus, the uFPA data are in the form of their geometric means ± the geometric standard deviation (SD). Other data are expressed as the arithmetic means and SD. These data were analyzed using an unpaired t test. The true negative rate of the test was defined as the percentage of patients in whom PE was excluded who had a negative test result. Cheap Diskus Advair
Results
Of the 100 consecutive patients, 71 were excluded: 64 with an abnormal V/Q scan, other than a high-probability interpretation, that was not defined further by PA; five patients receiving anticoagulants; and two patients who had undergone surgery within four days. The majority of the excluded patients (69 percent) had a V/Q scan interpreted as “low probability of PE,” which along with a clinical history was believed to be sufficient for exclusion of PE. There is evidence in the literature in support of this practice.
Twenty-nine patients were included in the final analysis: seven patients with PE (age range, 19 to 79 years, four female) and 22 who did not have PE (age range, 22 to 65 years, 15 female).

This entry was posted in Pulmonary function and tagged acute pulmonary embolism, chest roe, fibrin.
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