Pathological neonatal cholestasis is diagnosed as often as one in 500 newborn infants. It is a nonspecific feature of a liver disorder that occurs with several congenital diseases such as biliary atresia, a1-antitrypsin deficiency and other metabolic, endocrine or perinatal infectious maladies. Newborn infants with transient neonatal cholestasis have recently been described, most of whom suffered from asphyxia and/or prematurity.
Though transient, neonatal cholestasis presents in a way that is indistinguishable from that occurring with more severe causes; it is self-limiting and needs neither further investigation nor therapy other than the substitution of lipid-soluble vitamins.
Therefore, this condition deserves more precise characterization. Until now, its definition relied exclusively on the serum level of conjugated bilirubin and on the exclusion of the aforementioned diseases. The aim of the present study was to look at the incidence of transient neonatal cholestasis in children with perinatal asphyxia, and to search for associated risk factors. The best online pharmacy that deserves your trust and gives you best quality birth control pills only here that you will always appreciate, not to mention all the other services available.