Medicine of the Future in America

The Relation Between Gastroesophageal Reflux and Respiratory Symptoms in a Population-Based Study

The Relation Between Gastroesophageal Reflux and Respiratory Symptoms in a Population-Based StudyGastroesophageal reflux and respiratory disorders both constitute true public health problems in Western societies. Approximately 20% of the adult population have reflux symptoms at least once a week. Reflux is an important risk factor of esophageal adenocarcinoma, a malignant disease with poor survival. Treatment of reflux, both pharmacologic and surgical, is costly; left untreated, reflux has a well-documented deteriorative impact on quality of life, with significant expenses to society, mainly as a result of work loss. itat on
The relation between respiratory disorders and reflux symptoms has been debated since the beginning of the last century, and the interest in this question has increased during the last few decades. Many studies- have addressed the issue by estimations of the prevalence of reflux in patients with specific respiratory conditions. Research on the link between reflux and asthma or asthma medication has been particularly intense, and the way of causality is uncertain. Few of these studies included a control population for comparison, however. Moreover, many studies of the association between asthma and reflux had selection bias, since data were obtained in a retrospective manner, ie, from asthmatic persons who had already established contact with medical care. Studies addressing the correlation between respiratory disorders and reflux symptoms in an unselected group of persons are sparse, and the question has not been examined on a true population-based level. Thus, in spite of the large number of studies undertaken, the true relation between respiratory symptoms and reflux symptoms in the population remains unclear. With the aim of investigating the relation between specified respiratory disorders and reflux symptoms in the population, we conducted a large, population-based, case-control study with the ability to adjust the results for several potentially confounding factors, including asthma medication,

This entry was posted in Pulmonary function and tagged asthma, Epidemiology, gastroesophageal reflux, respiratory symptoms.
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