Medicine of the Future in America

Sleep in PostPolio Syndrome: Results (Part 1)

The 13 patients (Table 1) with a mean number of years since polio onset of 39.6 years ±5.8 SD were studied. Group 1, (36.6±0.4 SD years since onset of polio), had all required ventilatory support at the initial onset of polio in the form of a tank respirator for an average of 9.3 months (range 1.5 to 18 months) prior to attempted weaning. Patients 3 and 4 could not be weaned and required the rocking bed only for nocturnal support but otherwise breathed spontaneously while sitting up. The remaining patients were weaned completely for an average of 8.6 years (range ten to 168 months) after which they were started on rocking beds at night. At the time of the study, all the patients were using nocturnal respiratory assistance for a mean of 10.7 hours per day (range ten to 14 hours) (Fig 2). All of the patients had subjective complaints of respiratory or sleep problems.
There were 39.4 ± 7.3 years since the onset of polio in the eight group 2 patients. Five of the eight did not require any respiratory assistance at the onset of the disease and three of the patients required ventilator support for less than one month in a tank respirator. Subsequently, none of these individuals had used any form of respiratory assistance. These patients had symptoms of fatigue and excessive daytime sleepiness and nonrestorative sleep. ventolin inhaler

 Table 1—Patient Data 

ABGs Pulmonary Functions
Patient Sex Age Pa02 PaCO, pH VC FEV, FRC TLC RV
Group 1 (rocking bed patients)
1 M 59.1 71 42 7.45 33 40 63 53 87
2 M 63.0 76 50 7.38 27.5 33.4 62 49 89
3 M 57.8 74 53 7.39 15.1 11
4 F 58.7 80 45 7.39 27.8 23.9 55.3 46.2 78
5 F 61.5 73 46 7.41 24.6 23.4
MEAN 60.2 74.8 47.2 7.404 25.4 26.0 60.1 49.4 84.7
± SD 2.1 3.4 4.3 0.028 6.5 11.7 4.2 3.4 5.9
Group 2a (no sleep abnormality)
6 F 30.5 71 42 7.45 44.2 54.5 104.8 102 68.8
7 F 70.8 88 42 7.41 70.1 82.7 82.9 82.9 102.5
8 F 46.4 71 45 7.41 33.3 26.7
MEAN 49.4 76.7 43.0 7.423 49.2 54.6 93.9 92.5 85.7
±SD 20.3 9.8 1.7 0.023 18.9 28.0 15.5 13.5 23.8
Group 2b (sleep abnormalities)
9 M 65.5 81 39 7.39 76.5 64.4 76.3 83.6 96.4
10 F 60.6 93 34 7.47 99.2 81.8 92.9 94.8 87.8
11 F 57.8 82 34 7.51 81.2 110 66 75.5 66
12 F 48.1 85 41 7.39 38.1 34.9 65.4 57.9 97.3
13 F 66.1 67 43 7.46 37 40 81 62 101
MEAN 59.8 81.6 38.2 7.444 66.4 64.2 76.3 74.8 89.7
±SD 7.3 9.4 4.1 0.053 27.7 27.5 11.4 15.2 14.1

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This entry was posted in PostPolio Syndrome and tagged Hypopnea, Sleep, Sleep abnormalities.
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