Medicine of the Future in America

Respiratory Symptoms and Lung Function in Animal Feed Workers: Respiratory Symptoms and Lung Function

Respiratory Symptoms and Lung Function in Animal Feed Workers: Respiratory Symptoms and Lung FunctionChronic bronchitis was significantly related to cumulative dust exposure, shortness of breath was related to present dust and present endotoxin exposure (Table 5), whereas wheezing was related to cumulative dust and endotoxin measures. Since both respiratory symptoms and lung function were different among exposure categories with respect to present dust exposure, we investigated whether symptoms were related to lung function parameters using two logistic regression analyses (one with flow volume parameters, one with impedance parameters). These analyses revealed that chronic bronchitis is significantly associated with a decrease in FEVi and MMEF fully purchase antibiotics online. Shortness of breath was significantly related to changes in lung function (R8, frequency dependence of resistance [FD], and FEVi). As a group, individuals with asthmatic episodes differed from others in terms of impedance parameters, but not in terms of exposures.
This study provides further evidence that organic dust exposure in the animal feed industry may induce airflow obstruction and respiratory symptoms.’ Lung function in exposed workers was found to be inversely related to both present and cumulative exposure to inspirable dust. A significant exposure-re-sponse relationship was observed between present dust exposure and lung function parameters from both techniques applied. On the other hand, all impedance parameters correlated significantly with cumulative dust exposure, while only FEF25 was a significant descriptor of airflow obstruction due to cumulative dust exposure. Present and cumulative exposure to airborne endotoxin proved to be a better descriptor than total dust of changes in all lung function parameters.
Dust exposure in fodder dust industry in the Netherlands has been studied elaborately by Smid and coworkers. Because we had no indication that exposure levels in our fodder dust facilities would differ significantly from those reported by Smid et al, the characterization of dust exposure itself was conducted by measuring endotoxin levels in the dust.

Table 5—Statistical Significance of Factors (Exposure, Spirometric, and Impedance) in Relation to the Respiratory Complaints

Exposure Flow Volume Impedance
Chronicbronchitis Cumulativedust FEVi,MMEF
Breathlessness Present dust Present endotoxin FEVX R8, FD
Wheezing(ever) Cumulative dust Cumulative endotoxin
Asthmaticattacks Я8, X8
This entry was posted in Pulmonary function and tagged airflow obstruction, early diagnosis, endotoxin, flow volume curves, forced-oscillation technique, inspira-ble dust, occupational.
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