Medicine of the Future in America

Long-term prognosis of early-onset Crohn’s disease: Intestinal resections (Part 1)

early-onset Crohn’s diseaseAfter diagnosis of early-onset Crohn’s disease, mean time to the first intestinal resection was 4.2 years (range to 20 years). For males, mean time to the first resection was 4.2 years (range to 20 years), and for females, 4.1 years (range to 19 years). After the first resection, mean time to the second resection was 6.6 years (range to 25 years). For males, mean time to the second resection was 6.7 years (range to 23 years), and for females, 6.6 years (range to 25 years).

Table 2 further shows males and females with early-onset disease who required an intestinal resection for defined periods from the time of diagnosis to that of the first resection. As shown, for both sexes, the first intestinal resection was performed within the first two years after diagnosis in approximately 50%. Table 3 also shows the number of males and females who required a second intestinal resection for defined periods after the first resection. The second intestinal resection was also required within two years in approximately one-third of both male and female patients. Best quality drugs cheap: find ventolin inhalers click here and discover best deals online.

TABLE 2 Time from diagnosis to first resection

Time Males (n=58) n (%) Females (n=68) n (%)
0 to 2 years 25 (43.1) 35 (51.5)
3 to 5 years 15 (25.9) 14 (20.2)
6 to 10 years 13 (22.4) 12 (17.6)
11 to 20 years 5 (8.6) 7 (10.3)

TABLE 3 Time from first resection to second resection

Time Males (n=24) n (%) Females (n=28) n (%)
0 to 2 years 8 (33.3) 9 (32.1)
3 to 5 years 7 (29.2) 5 (17.9)
6 to 10 years 5 (20.8) 9 (32.1)
11 to 20 years 3 (12.5) 4 (14.3)
Over 20 years 1 (4.2) 1
This entry was posted in Crohn’s disease and tagged Clinical behaviour of Crohn’s disease, Crohn's disease, Granulomatous colitis, Natural history of Crohn’s disease, Vienna classification.
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