Medicine of the Future in America

Detection of Fungi and Other Pathogens in Immunocompromised Patients by Bronchoalveolar Lavage: Discussion (Part 5)

Detection of Fungi and Other Pathogens in Immunocompromised Patients by Bronchoalveolar Lavage: Discussion (Part 5)However, no patient in the present series had this organism demonstrated by smear or culture. Since the present report includes only patients with diffuse radiologic infiltrates, we excluded two cases of M avium-intracellulare presenting with localized infiltrates during the period of study. buy antibiotics online

More recently we have begun to examine induced sputum for the presence of Pneumocystis in AIDS patients using both Pap- and GMS-stained cytologic preparations and fluorescein labeled monoclonal antibodies against Pneumocystis. This approach, as shown by others, may decrease the number of patients that require diagnostic BAL, although one study suggests that in areas with only a moderate incidence of AIDS, BAL may be a better diagnostic approach. Since C immitis can also be diagnosed by sputum examination, this approach may enable the diagnosis of coccidioidomycosis to be made in a portion of patients with that infection as well. However, the present study suggests that non-AIDS patients are less likely to have diseases, such as Pneumocystis pneumonia, that can be detected by sputum examination alone. The diagnosis of noninfectious pulmonary infiltrates in these immunocompromised patients usually requires BAL examination rather than sputum cytologic study.

This entry was posted in Bronchoalveolar Lavage and tagged Bronchoalveolar Lavage, Cytomegalovirus, Pathogens, Pneumonia.
Copyright © 2012 Medicine of the Future in America www.perfexis.org