Medicine of the Future in America

Detection of Fungi and Other Pathogens in Immunocompromised Patients by Bronchoalveolar Lavage: Discussion (Part 4)

Nevertheless, in all such cases the pneumonia was effectively treated without therapy directed toward the virus. Also, autopsies on five patients who had cytomegalovirus cultured from their BAL failed to reveal histologic changes consistent with cytomegalovirus pneumonia or viral inclusions in lung tissue. However, most of the cytomegalovirus was in AIDS patients with Pneumocystis (13/21), and the two transplant patients with cytomegalovirus had no Pneumocystis attributed to this virus. buy flovent inhaler

Our inability to detect Mycoplasma sp in any case studied is curious in view of a previous report from the same city that preceded the present study. In that report approximately 20 percent of the immunocompromised patients had Mycoplasma recovered from BAL fluid. We are unable to explain the absence of Mycoplasma in the present series, even though the same culture methods were employed. Mycobacterium tuberculosis and Mycobacterium avium-intracellulane have been reported in BALs from other institutions, and we have seen M avium-intracellulare infection at autopsy in several AIDS patients. The incidence of mycobacteria in BALs of immunocompromised patients without AIDS has been reported to be 3 to 4 percent and 9 to 12 percent in AIDS patients.

This entry was posted in Bronchoalveolar Lavage and tagged Bronchoalveolar Lavage, Cytomegalovirus, Pathogens, Pneumonia.
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