Medicine of the Future in America

Category Archives: PostPolio Syndrome - Part 2

Sleep in PostPolio Syndrome (Part 3)

We recorded the EEG, EOG, and EMG from surface electrodes. Arterial oxygen saturation was continuously recorded with a pulse ear oximeter set on its fastest response. Respiratory movement was monitored by inductance plethysmography with transducers placed around the chest and abdomen. The ECG and heart rate were continuously recorded from standard limb leads. Airflow was detected by monitoring expired CO, at the nose and mouth through nasal/oral CO, cannula attached to a CO, analyzer. All variables were continuously recorded on a polygraph at a paper speed of 10 mm/s. A microcomputer continuously monitored airflow and respirator)’ movement and stored Sa02 and heart rate twice for each complete respiratory cycle on a mass storage medium. The computer generated a binary stamp on the polygraph so that the polygraph data and computer data could be synchronized during later analysis. Continue reading

Sleep in PostPolio Syndrome (Part 2)

These 13 patients (Fig 1) were divided in two groups: group 1 consisted of five patients (two women, three men with a mean age of 60.2 years ±2.1 SD, range 58 to 63) who were on rocking beds only at night for respiratory assistance (Fig 2); group 2 consisted of eight patients (seven women and one man with a mean age of 55.9 years ± 13.3 SD, range 30 to 70 years) who were not receiving any respiratory assistance. This latter group was broken down post hoc into: 2a, those who showed no sleep abnormalities and required no treatment, and 2b, those who had sleep abnormalities and required treatment. The degree of physical disability is shown in Figure 1. Continue reading

Sleep in PostPolio Syndrome (Part 1)

Sleep in PostPolio Syndrome (Part 1)Patients who had poliomyelitis were frequently clinically stable three to four decades after the acute attack. Deterioration of overall function then occurred in approximately 25 percent of the patients. Two mechanisms have been hypothesized to cause the worsening when it involved respiration-superimposi-tion on an already compromised respiratory system by the effects of aging, or the postpolio syndrome. The features of this syndrome are fatigue, new weakness in muscles (both those originally affected and those unaffected), pain in muscles or joints, dysphagia, and hypoventilation. Since apnea during sleep has been described in postpolio patients, we wondered whether abnormal sleep related to impaired ventilation may cause some of the symptoms of the syndrome. Continue reading

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